Leo turns the sisters into Greek goddesses so they will be able to vanquish mythic giants Piper's life is turned upside down when Leo accepts the call to become leader of the Elders.
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Billie unknowingly contacts a demon posing as a human (Sean McDermott) Piper tries to deal with Leo's absence Paige is able to connect with Henry (Ivan Sergei).
When the Angel of Death returns seeking Leo, the Charmed Ones try to use a spell to hide Leo, but it misfires and everyone suddenly looks like Leo.
The Charmed Ones help agent Murphy track a demon who escaped from the government's custody and learn that a virus is causing magical beings to run amok.
Agent Murphy gives the Charmed Ones their first Homeland Security case Phoebe and Billie discover a belt that gives Billie superpowers.
Paige's plan to get her job back as a social worker changes when her Whitelighter father, Sam (Scott Jaeck), asks for her help with his charge.
Billie must overcome the painful childhood memory of her sister's kidnapping before she can face the Dogan (Eric Steinberg) and prove her worth.
Billie uses her powers to save an innocent and is caught by Agent Murphy of Homeland Security, who has suspected all along that she and the others are involved in supernatural activities.
A demon disguised as a "perfect" mother attempts to befriend Wyatt with the intention of kidnapping him.
When Piper interviews with a corporate recruiter, a background check reveals that the physical appearance she adopted was that of a woman wanted for murder.
Pandora's Box falls into the hands of a shape-shifting demon (Michelle Hurd) who intends to open it and release all of its sorrows into the world, sending the sisters on a search for Hope (Brooke Nevin).
Zankou uses his underlings to lure the sisters out of their house, so he can search for the Nexus and release the Shadow, the ultimate power.
Piper is attacked by demons and winds up in a coma, and as she hovers between life and death, her spirit meets Cole (Julian McMahon), who says he is trying to help restore Phoebe's faith in love.
When Inspector Morris believes his friend is possessed, the Charmed Ones investigate and find that a victim of a fire in 1899 has taken control of Mike.
When Paige tries to hire a new professor for the Magic School, one of the candidates, Drake (Billy Zane), turns out to be an ex-demon who made a deal with a sorcerer to become human.
Leo learns that the Charmed Ones' conflict-free world comes with a high price, so he teams with Zankou (Oded Fehr) to stop the Avatars and reverse the change.
While the Avatars prepare to transform the world into a utopia, Brody is kidnapped by Zankou and forced to place a paranoia spell on the Charmed Ones.
When Piper tries to switch powers with Phoebe so that she can see Phoebe's vision for herself, the demon Zankou (Oded Fehr) attacks the women and causes their abilities to be transferred to innocents.
Grams puts a spell on the brothers to end their rivalry, but the spell turns the Charmed Ones into bickering teens Leo consults a demonic seer (Charisma Carpenter) to find out who is behind the attack on Wyatt.
When a bored student at the Magic School accidentally conjures up Lady Godiva and Lord Dyson, the Charmed Ones must keep Dyson from killing Lady Godiva before she can go back in time and complete her famous ride.
After Leo and Piper inadvertently receive the powers of Hindu gods, Phoebe and Paige must keep them from consummating their love in order to save the universe.
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