Pandora's Box falls into the hands of a shape-shifting demon (Michelle Hurd) who intends to open it and release all of its sorrows into the world, sending the sisters on a search for Hope (Brooke Nevin).
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A monk (Clyde Kusatsu) teaches Billie how to use her power of projection to find her sister Phoebe celebrates her independence by throwing a housewarming party that gets out of control.
Phoebe realizes that she must move on with her life and signs a lease for a new apartment Paige considers moving in with Henry Piper tries to maintain control after losing Leo.
Paige tries to help Henry (Ivan Sergei) get his parolee, Nick, a loan at a bank, but when it denies him the loan, Nick crashes his car into the bank and holds everyone hostage.
Billie unknowingly contacts a demon posing as a human (Sean McDermott) Piper tries to deal with Leo's absence Paige is able to connect with Henry (Ivan Sergei).
When the Angel of Death returns seeking Leo, the Charmed Ones try to use a spell to hide Leo, but it misfires and everyone suddenly looks like Leo.
The Charmed Ones help agent Murphy track a demon who escaped from the government's custody and learn that a virus is causing magical beings to run amok.
Agent Murphy gives the Charmed Ones their first Homeland Security case Phoebe and Billie discover a belt that gives Billie superpowers.
Paige's plan to get her job back as a social worker changes when her Whitelighter father, Sam (Scott Jaeck), asks for her help with his charge.
When a classmate killed in front of Phoebe comes back from the dead to blame her, she becomes guilt-ridden and vulnerable, creating an opportunity for Zankou to steal the Book of Shadows.
The Charmed Ones do not realize that baby Wyatt's new imaginary friend is actually the demon Vicus, who is trying to win Wyatt's trust to convert him to evil.
A powerful sorceress (Suzanne Krull) casts a spell on Phoebe so their souls switch bodies and Phoebe winds up trapped in the Underworld Paige is in a quandary when her first charge (Seamus Dever) appears to be lost to the dark side.
Pandora's Box falls into the hands of a shape-shifting demon (Michelle Hurd) who intends to open it and release all of its sorrows into the world, sending the sisters on a search for Hope (Brooke Nevin).
Zankou uses his underlings to lure the sisters out of their house, so he can search for the Nexus and release the Shadow, the ultimate power.
Piper is attacked by demons and winds up in a coma, and as she hovers between life and death, her spirit meets Cole (Julian McMahon), who says he is trying to help restore Phoebe's faith in love.
When Inspector Morris believes his friend is possessed, the Charmed Ones investigate and find that a victim of a fire in 1899 has taken control of Mike.
When Paige tries to hire a new professor for the Magic School, one of the candidates, Drake (Billy Zane), turns out to be an ex-demon who made a deal with a sorcerer to become human.
Agent Brody and Paige discover that the demon Sarpedon is capturing innocents' Guardian Angels and using them to protect himself from the New Power.
The Charmed Ones try to prove Leo's worth to the Elders after their suspicions of him result in the appointment of a new Whitelighter.
A demon tries to destroy his human half by killing his remaining blood relatives, so Paige casts a spell that inadvertently blocks all death from occurring, angering the Angel of Death (Simon Templeman).
Phoebe and Piper steal the golden chalice in order to bring the fountain of youth to life and save Paige from a curse that an 18th-century pirate gave to her.
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