A mother of two young children was found dead in her bedroom. Her death was ruled a suicide - but when investigators learned she had almost died in a house fire three years earlier, they decided to take another look at the evidence.
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A woman appears to have lost control of her SUV and plunged down an embankment into a shallow creek. But investigators suspect foul play when they find snowy footprints leading from the crime scene.
In 1994, a human skull retrieved from an Ohio pond reveals a ghastly crime. Markings on the skull indicate that the victim had been stabbed multiple times and that the teeth had been removed with needle-nose pliers.
In 1996, Indiana police identified Richard Alexander as the "River Park Rapist" who assaulted four women that year. Later, DNA analysis casts doubt on his conviction.
A young, attractive hairdresser was sexually assaulted and murdered in her own beauty salon. The evidence at the crime scene didn't match any of the suspects and the case went cold for ten years.
On a cold December night in 1993, Rose Larner stopped in a convenience store on her way to her boyfriend's house. She was never seen or heard from again. A tiny clue found years later revealed a tragic tale of drugs, romance and revenge.
A man who had committed crimes including murder was not caught. Almost 50 years later, advances in technology and handwriting analysis uncovered the criminal.
Who was the sexual offender who murdered two boys in Nebraska? The key to stopping him would be the unique composition of the "junk rope" he used to tie his victims.
When a serial killer was terrorizing the city of St. Louis, the FBI didn't need lab tests, fingerprints or any of the usual methods. All they needed was a computer.
A mother of two young children was found dead in her bedroom. Her death was ruled a suicide - but when investigators learned she had almost died in a house fire three years earlier, they decided to take another look at the evidence.
In 1995, police in San Diego, California are baffled by a pair of hands found in a dumpster. Through further investigation, they determine that the hands are those of missing person Don Hardin.
An infant was rushed to the emergency room with serious breathing problems. Within months, there were more than 30 cases. Doctors searched frantically for the cause and a cure.
When a talented television news anchor is shot to death outside her home, it appears to be a crime of passion perpetrated by an obsessed fan.
After inspecting storm damage to a home in Tampa, an insurance assessor simply disappeared. Thirty hours later, her body was found in a nearby river. But the killer had been careless.
A brilliant young architect became ill and died just before she was to testify in a criminal trial. The autopsy revealed she'd been poisoned with arsenic. Investigators had to determine which person who knew her had a motive for murder.
A murder investigation in Florida crosses jurisdictions from New York and Jamaica. The police rely on cell phone mapping, wiretapping and a host of forensic evidence to link a suspect to a murder.
A California teen went missing. Police suspected she'd run away until her body was discovered in a ditch.
A man was killed in a car crash, but the evidence led investigators to believe it was not an accident.
In 1992, 22-year-old Dawn Bruce is brutally murdered in her Virginia apartment. Investigators notice a blood smear on a pillowcase that appears to have been made by one of the killer's fingers.
A car carrying three men pulls up alongside another on an Alaskan highway and fires shots, leaving a passenger dead. One of the passengers in the killer's car agrees to testify against his friends. The resulting trials don't end the carnage.
In 1993, young mother Tammy Tatum was sexually assaulted and murdered in her Longmont, Colorado apartment.
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