When Matty's goddaughter and her boyfriend are killed in a San Francisco park, Mac and the team investigate the crime and start to suspect that the 1970s Zodiac Killer has returned.
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When Mac and the team are blamed for a terrorist bombing, the Phoenix Foundation is forced to disavow them the team must clear their names without support from back home.
While Mac and Jack are tracking a dangerous fugitive, a family of bounty hunters kidnap him Bozer and Riley try to hack into Jack's CIA file.
When Matty's goddaughter and her boyfriend are killed in a San Francisco park, Mac and the team investigate the crime and start to suspect that the 1970s Zodiac Killer has returned.
Mac and Jack must track down a corrupt FBI agent who has framed a man for murder everyone on the team is terrified to get a performance review from the tough new boss.
While returning from capturing a war criminal, Mac and Jack's helicopter crashes, allowing the prisoner to escape.
MacGyver hunts a U.S. government mole who is leaking classified information to the organization trying to take down the Phoenix Foundation Sarah comes back to help with the mission Mac can't tell which side Nikki is on.
MacGyver and Jack must find Riley after she disappears and hacks into the NSA Bozer embarks on his first mission Jack reveals his history with Riley's mother.
A notorious street artist becomes a suspect when corpses are used in macabre graffiti art in Detroit Dr. Lewis tries to balance work and her relationship with her fiancé.
When a robbery-homicide leaves three restaurant employees dead, a cold case that occurred in the same town six years earlier could yield a lead.
The team suspects a jilted unknown subject is responsible when brides are murdered on the eve of their nuptials.
The team must find the person responsible for a sarin gas attack on a Los Angeles bus before a larger incident occurs.
The BAU interviews candidates to take the opening left by Kate's departure the team tracks a serial killer who leaves behind evidence that indicates a person intent on revenge.
The team suspects Kate's niece and her friend were kidnapped by an online predator involved in sex trafficking and race to find them before they are hurt.
The BAU tracks a vigilante in Los Angeles who is shooting people with possible ties to criminal activity.
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