A deadly accident at a naval base exposes a unit of Seabees to a super virus and leaves the rest of the base and the city of New Orleans at risk for an outbreak Wade is infected with the virus and given hours to live.
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McGarrett joins Junior and his SEAL team on a mission to capture an elusive person who is holding his mentor hostage Gerard Hirsch and Kamekona help Grover and Tani on a murder case involving art stolen by Nazis during World War II.
McGarrett and Five-0 take on the mob when a former boss is killed Junior's friend is on the run after witnessing the murder.
Duke is forced to steal crucial evidence from the police locker in exchange for his kidnapped granddaughter Jerry goes undercover at a mental health facility to solve a murder.
Harry Langford enlists McGarrett and Danny's help to track down a teenage British royal who has run away while under his protection Grover, Tani and Junior work a 25-year-old murder case after a mysterious videotape arrives at headquarters.
When a powerful earthquake hits Los Angeles, Team Scorpion must prevent a pinched gas line from causing a massive explosion.
The members of Team Scorpion are asked to help NASA with a top-secret rocket launch, but they must sabotage their own mission when Walter's date finds a bomb strapped to her chest.
Sylvester's father, a retired general, asks the team for help when he thinks a dictator in Africa has uncovered weapons of mass destruction from World War II.
Pride starts to doubt evidence suggesting homeless kids murdered a petty officer.
Wade's son asks Pride for help after being attacked and discovering his girlfriend is missing Pride must meet with a therapist to discuss his process for solving cases.
The team investigates after a clinical trial in which brain implants are put into veterans is hacked Patton must work alongside his ex-wife, who spearheads the project.
The murder of a petty officer leads the team to a woman who is targeting men with high security clearance LaSalle's father arrives to discuss the family business.
Sebastian is placed on administrative leave after being questioned by the FBI about a foot chase Pride and the team attempt to clear Sebastian's name.
The team investigates the copycat murder of an unsolved case from 150 years ago that spawned a legendary ghost story Gregorio is spooked when the case is connected to a recent séance and a local medium.
The team joins forces with FBI Director Isler after a Russian operative with intelligence on sleeper agents disappears Tammy partners with former sleeper agent Eva Azarova to assist in the disappearance.
Pride listens in on a wiretap of Mayor Hamilton the NCIS team investigates when Navy weapons get stolen in a train heist featuring musical performances by Sheryl Crow.
LaSalle must investigate his former partner in the Vice unit after the NCIS team finds a link between an international drug ring and the New Orleans Police Department Rita looks into a connection between the mayor and illegal activity in Clearwater.
A deadly accident at a naval base exposes a unit of Seabees to a super virus and leaves the rest of the base and the city of New Orleans at risk for an outbreak Wade is infected with the virus and given hours to live.
Tammy is reunited with her ex-husband, Ethan McKinley - who embezzled millions in Katrina relief funds - after he's tied to the murder of a crime boss' son.
Toby and Michelle search for a dangerous gang while feeling the pressure of the new police superintendent.
Toby and Michelle investigate a string of high-tech thefts in Vancouver.
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