Mark, Jesse, and Amanda are trapped in a hotel when it's quarantined after a deadly virus is released. They struggle to contain the virus, while at the same time trying to locate its origin.
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MacGyver joins an expedition searching for the lost civilization in the hidden valley of Shangri-La.
MacGyver fights to save a housing project after tenants have been forced out of their homes by corrupt money-hungry landlords.
While working at the Challenger Club, MacGyver finds he must save the local gang kids from Minton, the local gun supplier, who is planning to kill all the gang members as well as letting Brian Jefferies take the wrap for a murder he did not commit.
MacGyver helps train an old friend who is trying to make a comeback as a boxer.
A retired silent film comedian, Pinky, donates his films to the Phoenix Foundation and together, he and MacGyver, find themselves caught in a deadly trap woven by a special effects master named Neil who is out for revenge.
A bump on the head takes MacGyver back to 7th century England where he searches for his roots and rescues a beautiful maiden from an evil queen.
Several murders occur while Tibbs' former partner is visiting.
A woman's (Susan Blakely) claim she murdered her father because of incest shocks Gillespie.
Gillespie is stalked by a killer who re-created a bizarre 20-year-old murder.
An escaped killer and his girlfriend take Althea and a child hostage to ensure a getaway.
A man's six wives become murder suspects when he dies of food poisoning.
Though Tibbs was nearly killed, Gillespie still can't prove Epson is a drug trafficker.
Seemingly random events become connected when Gillespie's friend is shot.
A serial killer is on the loose at Community General, targeting both patients and doctors. Dr. Sloan, Steve, Amanda, and Jesse notice that a murder takes place every hour on the hour.
Mark, Jesse, and Amanda are trapped in a hotel when it's quarantined after a deadly virus is released. They struggle to contain the virus, while at the same time trying to locate its origin.
A retiring detective is still obsessed with catching a murderer known as "The Clown Killer".
When resident Paul Brewer is killed, it's the second murder in a month at the exclusive gated community, Hillview Estates. With no leads on the killer, Steve goes undercover as Dr. Steve Brewer, a community resident.
Jesse and Susan are on their way to Mount Carmel for a romantic getaway weekend but detour to a fishing town when their car breaks down. They grab a bite at the local diner when Susan sees a man she used to know.
Steve investigates a series of seemingly unconnected murders committed by terminally ill patients, to find the hidden thread.
Steve joins his troubled detective partner in a rehab facility for cops on the edge.
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