Five

Jeanne Tripplehorn as Pearl Josh Holloway as Bill Austin Nichols as Edward Taylor Kinney as Tommy Rosario Dawson as Lili Annie Potts as Helen Xander Berkeley as Peter Scott Wilson as Bill (Older) Ravi Patel as Dr. Desai Josh Dallas as Henry Jennifer Morrison as Sheila Tony Shalhoub as Mitch Alan Ruck as Sam Jarente Patricia Clarkson as Mia Lyndsy Fonseca as Cheyanne Ginnifer Goodwin as Charlotte Carla Gallo as Laura Jenifer Lewis as Maggie Kirk Baily as Scott Aisha Hinds as Bernice Kathy Najimy as Rocky Romy Rosemont as Lynne Bob Newhart as Dr. Roth Emily Skinner as Sally Tracee Ellis Ross as Alyssa Jeffrey Tambor as Danny David Eigenberg as Lenny Ava Acres as Pearl at age 7

Whitney James Makeup Department Head Lorne Balfe Original Music Composer Marta Kauffman Creator, Executive Producer Zene Baker Editor Alicia Keys Director Patty Jenkins Director Kristin Hahn Executive Producer Penelope Spheeris Director Lynzee Klingman Editor Mary Claire Hannan Costume Design Paula Wagner Executive Producer Jennifer Aniston Director, Executive Producer Tami Reiker Director of Photography Eric Alan Edwards Director of Photography Nellie Nugiel Producer Demi Moore Director