Trailer
Cast
Sarah Silverman
Self
Laura Silverman
Self (segment "Knickers")
Jade Catta-Preta
Mother (segment "Lisa")
Nick Rutherford
Father (segment "Lisa")
Kate Freund
Prostitute (segment "CCDF")
Jordan Peele
Self (segment "Absorption")
Armen Weitzman
Mailman
2 Chainz
Self (segment "Absorption")
Hannah Hart
Bride 4 (segment "Absorption")
Jack Vale
Groom 1 (segment "Absorption")
Michael Daniel Cassady
Self (segment "Lisa")
Natasha Leggero
Girl 2 (segment "Lisa")
Grace Helbig
Bride 5 (segment "Absorption")
Rasika Mathur
Bride 3 (segment "Absorption")
Lauren Lapkus
Girl 5 (segment "Lisa")
Trevor Eyster
Bad Guy 1 (segment "CCDF")
Issa Rae
Bride 2 (segment "Absorption")
Seth Rogen
Officer Durand (segment "Knickers")
Paul Rust
Self (segment "Lisa")
Nathan Barnatt
Homeless Man (segment "Lisa")
Nathan Fielder
Self (segment "Retro Video Arcade")
Kyle Dunnigan
Self
Brett Gelman
Self
Rob Schrab
Self
Kyle Pacek
Son (segment "Ham")
Sandeep Parikh
Groom 3 (segment "Absorption")
Lo Mutuc
Self
Keegan-Michael Key
Self (segment "Absorption")
John C. Reilly
Father (segment "Ham")
Kulap Vilaysack
Girl 3 (segment "Lisa")
Todd Glass
Self
Tig Notaro
Girl 4 (segment "Lisa")
Casey Ford Alexander
Bad Guy 2 (segment "CCDF")
Emily Maya Mills
Girl 6 (segment "Lisa")
Eric Wareheim
Self
Greg Davis Jr.
Groom 2 (segment "Absorption")
Mark Taormino
Band Member 2 (segment "Absorption")