Trailer
Cast
Rodger Bumpass
Joe Cramp / Announcer for Nerve News Network (voice)
Richard Steven Horvitz
Additional Character Voices (voice)
Abe Farrelly
Bus Girl #2
Nikki Tyler-Flynn
Nurse #2
Laurence Fishburne
Thrax (voice)
Eddie Barth
Conductor (voice)
Donald Fullilove
Doughnut (voice)
Rif Hutton
Charlie (voice)
Anne Lockhart
Female Red Blood Cell (voice)
Doug Stone
Police Officer Jamie (voice)
Steve Susskind
Mob Boss Germ (voice)
Keri Tombazian
Additional Character Voices (voice)
William Shatner
Mayor Phlegmming (voice)
Danny Mann
Musician Cell (voice)
Mickie McGowan
Brain Librarian (voice)
Joel Silver
Police Chief (voice) (uncredited)
Janis Dardaris
Additional Character Voices (voice)
Jackie Gonneau
Additional Character Voices (voice)
Bill Murray
Frank Detorre
Kevin J. Flynn
Docky's Clamshack Waiter
Chris Rock
Osmosis Jones (voice)
Elena Franklin
Shane Detorre
Kid Rock
Kidney Rock (voice)
Sherry Lynn
Trudy (voice)
Danny Murphy
Zookeeper Superintendent
Sean Gildea
Dreamy Photographer
Zen Gesner
ER Doctor #1
David Hyde Pierce
Drix (voice)
Ron Howard
Tom Colonic (voice)
Carlos Alazraqui
Spanish Germ (voice)
John Melendez
Artie (voice)
Jackie Flynn
School Janitor
John-Eliot Jordan
Pea Soup Manager
Herschel Sparber
Bruiser (voice)
Robert Wisdom
Big Germ (voice)
Chris Phillips
Firefighter Doug (voice)
Zak Penn
ER Doctor #3
Brandy Norwood
Leah (voice)
Molly Shannon
Mrs. Boyd
Jonathan Adams
Officer Tom (voice)
Paul Tuerpe
Additional Character Voices (voice)
Chris Elliott
Bob
Antonio Fargas
Chill the Flu Shot (voice)
Héctor Mercado
Additional Character Voices (voice)
Paul Pape
Male Red Blood Cell #2 (voice)
Al Rodrigo
Frank Police Department Walkie Talkie (voice)
Sally Brooks
Additional Character Voices (voice)