Trailer
Cast
William Shatner
Mayor Phlegmming (voice)
Kid Rock
Kidney Rock (voice)
Anne Lockhart
Female Red Blood Cell (voice)
Nikki Tyler-Flynn
Nurse #2
Ron Howard
Tom Colonic (voice)
Janis Dardaris
Additional Character Voices (voice)
Chris Phillips
Firefighter Doug (voice)
Keri Tombazian
Additional Character Voices (voice)
Laurence Fishburne
Thrax (voice)
Danny Mann
Musician Cell (voice)
Héctor Mercado
Additional Character Voices (voice)
Paul Pape
Male Red Blood Cell #2 (voice)
Steve Susskind
Mob Boss Germ (voice)
Jackie Flynn
School Janitor
Eddie Barth
Conductor (voice)
Donald Fullilove
Doughnut (voice)
Jackie Gonneau
Additional Character Voices (voice)
John Melendez
Artie (voice)
Sean Gildea
Dreamy Photographer
Zak Penn
ER Doctor #3
Abe Farrelly
Bus Girl #2
Bill Murray
Frank Detorre
John-Eliot Jordan
Pea Soup Manager
Sherry Lynn
Trudy (voice)
Mickie McGowan
Brain Librarian (voice)
Herschel Sparber
Bruiser (voice)
Danny Murphy
Zookeeper Superintendent
Brandy Norwood
Leah (voice)
Carlos Alazraqui
Spanish Germ (voice)
Doug Stone
Police Officer Jamie (voice)
Chris Elliott
Bob
Rodger Bumpass
Joe Cramp / Announcer for Nerve News Network (voice)
Richard Steven Horvitz
Additional Character Voices (voice)
Al Rodrigo
Frank Police Department Walkie Talkie (voice)
Jonathan Adams
Officer Tom (voice)
Kevin J. Flynn
Docky's Clamshack Waiter
David Hyde Pierce
Drix (voice)
Elena Franklin
Shane Detorre
Antonio Fargas
Chill the Flu Shot (voice)
Joel Silver
Police Chief (voice) (uncredited)
Robert Wisdom
Big Germ (voice)
Rif Hutton
Charlie (voice)
Paul Tuerpe
Additional Character Voices (voice)
Chris Rock
Osmosis Jones (voice)
Molly Shannon
Mrs. Boyd
Sally Brooks
Additional Character Voices (voice)
Zen Gesner
ER Doctor #1