Trailer
Cast
David Hyde Pierce
Drix (voice)
Bill Murray
Frank Detorre
Mickie McGowan
Brain Librarian (voice)
Héctor Mercado
Additional Character Voices (voice)
Paul Pape
Male Red Blood Cell #2 (voice)
Abe Farrelly
Bus Girl #2
Sean Gildea
Dreamy Photographer
Brandy Norwood
Leah (voice)
Molly Shannon
Mrs. Boyd
Paul Tuerpe
Additional Character Voices (voice)
Robert Wisdom
Big Germ (voice)
Rif Hutton
Charlie (voice)
Kevin J. Flynn
Docky's Clamshack Waiter
Zen Gesner
ER Doctor #1
William Shatner
Mayor Phlegmming (voice)
Carlos Alazraqui
Spanish Germ (voice)
Al Rodrigo
Frank Police Department Walkie Talkie (voice)
Elena Franklin
Shane Detorre
Rodger Bumpass
Joe Cramp / Announcer for Nerve News Network (voice)
Janis Dardaris
Additional Character Voices (voice)
John Melendez
Artie (voice)
Steve Susskind
Mob Boss Germ (voice)
Danny Mann
Musician Cell (voice)
Doug Stone
Police Officer Jamie (voice)
Kid Rock
Kidney Rock (voice)
Chris Elliott
Bob
Sally Brooks
Additional Character Voices (voice)
Herschel Sparber
Bruiser (voice)
Danny Murphy
Zookeeper Superintendent
Donald Fullilove
Doughnut (voice)
Jackie Gonneau
Additional Character Voices (voice)
Nikki Tyler-Flynn
Nurse #2
Chris Rock
Osmosis Jones (voice)
Laurence Fishburne
Thrax (voice)
Eddie Barth
Conductor (voice)
Keri Tombazian
Additional Character Voices (voice)
Anne Lockhart
Female Red Blood Cell (voice)
Antonio Fargas
Chill the Flu Shot (voice)
Jonathan Adams
Officer Tom (voice)
Ron Howard
Tom Colonic (voice)
Zak Penn
ER Doctor #3
Joel Silver
Police Chief (voice) (uncredited)
Chris Phillips
Firefighter Doug (voice)
John-Eliot Jordan
Pea Soup Manager
Richard Steven Horvitz
Additional Character Voices (voice)
Sherry Lynn
Trudy (voice)
Jackie Flynn
School Janitor