Trailer
Cast
Melanie Chartoff
Didi Pickles (voice)
Lacey Chabert
Eliza Thornberry (voice)
Tress MacNeille
Charlotte Pickles (voice)
Phil Proctor
Howard DeVille (voice)
Danielle Harris
Debbie Thornberry (voice)
Bruce Willis
Spike (voice)
Chrissie Hynde
Siri (voice)
Flea
Donnie Thornberry (voice)
Tony Jay
Dr. Lipschitz (voice)
Ethan Phillips
Toa (voice)
Nancy Cartwright
Chuckie Finster (voice)
Dionne Quan
Kimi Watanabe-Finster (voice)
Joe Alaskey
Lou Pickles (voice)
Julia Kato
Kira Watanabe-Finster (voice)
Tara Strong
Dil Pickles (voice)
Cheryl Chase
Angelica Pickels (voice)
Jodi Carlisle
Marianne Thornberry (voice)
Tom Kane
Darwin (voice)
E. G. Daily
Tommy Pickles (voice)
Kath Soucie
Phil DeVille / Lil DeVille / Betty DeVille (voice)
Tim Curry
Nigel Thornberry (voice)
Michael Bell
Drew Pickles / Charles 'Chaz' Finster, Sr. (voice)
Jack Riley
Stuart 'Stu' Pickles (voice)
Cree Summer
Susie Carmichael (voice)