The victim had ingested a massive amount of cyanide. An unlikely clue - a flaw on a mailing envelope - exposed a murderer who was willing to kill innocent people.
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In 2006, Nevada politician Kathy Augustine died mysteriously during a hard-fought re-election campaign and the medical examiner could neither isolate the cause of death.
The body of a young girl was discovered on isolated farmland near Delano, California. She had no ID, but police found mailbox keys in the pocket of her jeans.
The victim has been stabbed more than thirty times, and the crime scene is awash with her blood. Near her head, police discover a distinctive button with strands of thread still attached.
An 82-year-old woman was found dead. Clues on the victim's body would tell police what happened that night.
In 2002, funeral director Lonnie Turner, Sr. was found shot to death. His son Lonnie Jr. became the prime suspect, particularly after it was discovered that the murder was committed with his gun. However, he had an alibi for the time of the murder.
In one of the most brazen crimes of the 20th century, the chairman of the Coors Brewing Company was kidnapped.
A man was killed in a car crash, but the evidence led investigators to believe it was not an accident.
After shooting his victims in the head, the killer staged the scene, placed the incriminating evidence into a plastic bag and tossed it into the river.
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.
In 2004, Rebecca Barney and her soon-to-be ex-husband Fred were found shot to death in their Tulsa, Oklahoma, home, which had been set on fire.
An assistant manager of a Florida steakhouse is stabbed to death. It appears to be a robbery gone wrong.
In 2006, Texas real estate agent Sarah Anne Walker was found brutally murdered in a model home.
After the suspect was convicted of murder, he maintained his innocence through his 25 years in prison.
A serial killer was on the loose and police had to find him before he struck again. Their most promising lead was an unusual one: a bloody fingerprint on the body of one of the victims.
When court clerk Peter Porco doesn't report to his work in November 2004, a courts officer is ordered to the Porcos' family home in Bethlehem, NY.
Foul play is suspected when Fort Worth factory worker Glenda Furch disappears after completing her shift.
When a wealthy socialite died after falling down the stairs, witness accounts contradicted evidence. Investigators employed a physicist and an expert in accident reconstruction.
An aspiring model turned up dead and the prime suspect was her boyfriend. When he was eventually cleared, investigators had to dig deeper to find the perpetrator.
In 2000, construction manager Darrell North was found dead in his work trailer in Ft. Worth, Texas. When investigators arrived, they found that he had been stabbed 46 times.
Police are able to create a composite sketch of a man burnt beyond recognition. But tracking the killer is more challenging.
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