When an 11-year-old girl disappeared from a small town in a remote area of Alaska, investigators wondered if she'd been attacked by a bear or become lost in the dense woods.
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A teenager went missing after an evening of horseback riding. Her body was found a month later, three miles from her home. The killer unknowingly left trace evidence behind - tiny but unmistakable clues which pointed to him and him alone.
A woman was found dead on a golf course. The grass on the course was so distinctive, it had evidentiary value.
When two women from the same town were murdered in the same way, police feared a serial killer was on the loose. At first they thought the victims had nothing in common until they found tiny clues linking them to the same man.
In an affluent suburb, police were called to the scene of what appeared to be an accidental drowning.
A college student was found dead, and the evidence suggested he knew his killer. Three hairs and some microscopic cells helped police to unravel a web of lies, and find the motive for murder.
A car carrying three men pulls up alongside another on an Alaskan highway and fires shots, leaving a passenger dead. One of the passengers in the killer's car agrees to testify against his friends. The resulting trials don't end the carnage.
When a young woman disappeared, police feared she was the latest victim in a string of similar crimes.
The murder of a millionaire indicated robbery, but investigators wondered if there was something more.
An employee of a dry cleaner was raped and murdered in the store. Police turned to forensic science for the answers they needed.
A brilliant young architect became ill and died just before she was to testify in a criminal trial. The autopsy revealed she'd been poisoned with arsenic. Investigators had to determine which person who knew her had a motive for murder.
A Native American woman was brutally killed in the desert of New Mexico, and the crime scene was rich in forensic evidence: tire tracks, shoe impressions and even the murder weapons.
Emergency dispatch received a call from a man who said his girlfriend shot and killed herself. The autopsy revealed that the gunshot wound was not self-inflicted and the evidence on her body would give police a golden opportunity to catch her killer.
When police recovered the car of a missing man, they expected to find his body - but it wasn't there.
Police led an intense search and relied on forensics when the mother of two young children went missing.
When an elderly couple died in a suspicious house fire, their son became the prime suspect. Investigators turned to forensic science to determine if the fire had been set deliberately, or if it was an unfortunate accident.
A man riding a bicycle was fatally injured, and police believed he was the victim of a hit-and-run accident. Tiny clues found at the scene created a picture of the vehicle which struck him and led police to its driver.
A man who had committed crimes including murder was not caught. Almost 50 years later, advances in technology and handwriting analysis uncovered the criminal.
A neighbor watched as a man stabbed his wife, pushed her into the swimming pool and held her head under water.
Police are led on a wild goose chase when the wife of a prominent banker is kidnapped. An entomologist's unexpected discovery leads to a new suspect - and the realization that ordinary office equipment can leave extraordinary clues.
The murder of an American tourist in a Mexican resort draws law enforcement resources in both countries.
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