In 1991, Dorothy Donovan was murdered in her Dover, Delaware home and police are skeptical when her son Charles Holden stated that she was murdered by a hitchhiker he had picked up.
A murder trail turned cold, until police got a call from a woman whose husband, Gerald Powers, had a criminal past and a fondness for Chevy Berettas.
The crime scene was especially violent: A couple had been shot to death. Was their teenage daughter complicit?
Detectives search for the bombers of two churches in Illinois, hoping that the materials used in the remnants of the handmade bombs will offer the clues to catch the culprits.
In 1987, the death of Crystal Purcell was considered an accident. Then in 2001, Barbara Purcell called police to suggest that her estranged husband had killed Crystal.
A bullet-riddled car, a missing driver, and no witnesses, an ambush or a random attack the clue was something so tiny, it was measured in millionths of a meter.
A woman who was known to have suffered from depression took her own life. But her sister told police that she said if anything were to happen to her there would be a note in the china cabinet.
In 2000, the body of exotic dancer Rachel Siani was found beneath a New Jersey bridge. Investigators wondered if she had committed suicide.
An 82-year-old woman was found dead. Clues on the victim's body would tell police what happened that night.
A woman was found dead on the bedroom floor of her apartment. The crime scene yielded little of value and investigators wondered if they would find enough evidence to make a case.
A family break turns into a nightmare when the wife is found face-down in a lake with no idea whether it was murder, an accident or suicide, police turn to a new forensic technique.
An assistant manager of a Florida steakhouse is stabbed to death. It appears to be a robbery gone wrong.
When a man's story of a killing contradicted physical evidence, investigators turned to forensic science.
In 2000, teenager Tara Munsey went missing after a work shift at a Virginia restaurant. Did she run away, or was she the victim of foul play?
In 1999, Patrick McRae was found dead in his Des Moines home and the crime scene was awash with blood.
Police arrested a suspect for the death of a girl. But new technology proved the wrong man was behind bars.
When the number of bloodstains at a scene were abnormal, it was up to forensic scientists to find out why.
In 1989, the dead bodies of Joan Rogers and her two teenage daughters were found floating in Tampa Bay.
The medical examiner ruled a death an accident, but the detectives thought the evidence indicated otherwise.
In 2006, Nevada politician Kathy Augustine died mysteriously during a hard-fought re-election campaign and the medical examiner could neither isolate the cause of death.