In 1997, Kelly Eckart's car was found, with her belongings still in it, after she worked a late shift in Franklin, Indiana. Days later, her body was found in an isolated ravine.
In a tragic twist of fate, just days after the woman sold her home and moved to a modest trailer, a fire took both the trailer and her life. But the autopsy proved this was no accident.
A young woman is stabbed more than 100 times. The killer leaves DNA behind, but investigators must play a cat-and-mouse game to obtain a suspect's DNA to match.
Responding to a 2008 garage fire, Illinois emergency response discovered a man crushed beneath a truck.
Police are able to create a composite sketch of a man burnt beyond recognition. But tracking the killer is more challenging.
A brutal murder, lots of suspects and conflicting evidence but the forensics were clear on one thing: The killer knew his victim. And that alone gave investigators a head start.
The body of a young girl was discovered on isolated farmland near Delano, California. She had no ID, but police found mailbox keys in the pocket of her jeans.
In 1996, Derrick Duehren returned to find his Oregon home burned to the ground. His wife's charred remains were later found in the rubble.
A girl claimed she had been abducted. She recounted what happened but things didn't add up to police.
The victim had been sexually assaulted and stabbed to death on the beach. A pair of men's tennis shoes was discovered near her body.
The body of an attractive young woman was found a mile from her abandoned car. Police were especially concerned when they realized the victim had come to them for protection just two weeks earlier.
When a woman went missing, friends and family were determined to find her. Their worst fears were confirmed weeks later when her body was discovered.
In 2007, Shamaia Smith disappeared from the strip club she worked at in East Hartford, CT. Police look at various customers of the strip club, but focus on local businessman Kenneth Otto.
Paul Gruber's daughter suspected something was wrong when she received birthday cards addressed from her father, but written in a stranger's handwriting.
Tracey Frame, 35, was convicted of killing David Nixon in April 2002 after he planned to end their relationship.
A killer made great effort to obscure the shoe impressions left when he tracked blood on the floor, but he ended up creating new incriminating evidence...
In 2003, Tiffany Rowell and three of her friends were brutally murdered in affluent Clear Lake, Texas.
Responding to a 2008 garage fire, Illinois emergency response discovered a man crushed beneath a truck.
In 2006, Darlene VanderGiesen received threatening emails and then disappeared. Tracking the source of the emails led police to the home of Daphne Wright, where they believe a murder was committed.
An assistant manager of a Florida steakhouse is stabbed to death. It appears to be a robbery gone wrong.