In 2000, Judy Southern arrived home from work and was shot by a gunman waiting within. Her husband Allen arrived shortly afterwards, called 911 to report his wife had been shot.
A young woman attends evening church services... then disappears. When her abandoned car is found, the tank is empty and a gas can she kept in her trunk for emergencies is missing.
In 1993, young mother Tammy Tatum was sexually assaulted and murdered in her Longmont, Colorado apartment.
An investigation into the murder of a World War II veteran slowed to a halt when the prime suspect had a solid alibi. But a lucky break led to a shady character who wore distinctive boots.
When DNA proves that a man who practically admits to a brutal attack is innocent, police wonder why he is willing to take the blame.
A driver said he couldn't have hit and killed a pedestrian because his Jeep had been sold months ago.
A woman was brutally murdered in her home and the only witnesses to the crime were the family dogs. An expert in canine behavior was convinced the killer knew both the victim and the animals.
A security guard disappeared from his post without a trace his remains were found a year later in a remote camp site.
In 2008, college co-ed Jenna Verhaalen was found dead in her Bryan, Texas apartment. Petechial hemorrhages in her eyes indicated that she was strangled.
A Michigan State University grad student disappeared and was presumed dead. With the help of a professor of geological sciences, police hoped to get the "dirt" on her killer.
In 2005, David Castor suffered a slow, agonizing death over a period of days. His wife maintained it was suicide, even though it was done with antifreeze.
When a college student is reported missing, police believe their investigation will be like countless others.
A bomb, constructed to cause as much damage as possible, kills a victim with deadly force and flame. When a search yields some tiny clues, police are able to identify the killer.
The brutal murder of a state park employee over $2,000 rattles her co-workers and tourists while leaving police to sift through hundreds of leads.
When a car was found in a drainage ditch with two bodies inside, a fingertip torn from a latex glove would point investigators to both the crime scene and the killer.
When an off-duty policeman was shot dead, his fellow officers were determined to solve the crime. They needed clues to find the killer and they discovered them in tiny fibres and an asthma inhaler.
A Russian immigrant is found dead and a strange phone call to his office is the only lead investigators have.
Foul play is suspected when Fort Worth factory worker Glenda Furch disappears after completing her shift.
In the 1990s, the media dubbed Richard Rogers the "Last Call Killer" because he targeted men in gay bars.
In 2008, the body of Colorado real estate developer Alan Helmick was found by his wife, Miriam, who then became the prime suspect.