A killer is murdering and mutilating young women along the Route 40 corridor in Delaware, but after investigators set up an undercover operation, the hunter soon becomes the hunted.
In the 1990s, Louisiana is terrorized by multiple serial killers the Zachary Police Department discovers the key to solving their cases when a pattern emerges with personal items missing from each local victim.
A serial killer taunts Wichita, Kan., for decades by sending brazen letters and taking credit for horrific kills at the introduction of the computer era, the killer gets sloppy and accidentally leaves a digital clue.
The I-5 corridor in California is taken over by a brazen bandit who terrorizes the highway with a blitz of assaults and murders the only clue to the killer's identity is a specific athletic tape used to bind his victims.
Numerous women are found dead by the side of the road with a unique ligature that looks like a dog collar and leash detectives are stumped until a 17-year-old girl manages an escape from a vicious kidnapper, leading police to a serial killer.
Police find a string of murdered women in shallow graves in very remote areas of the Alaskan wilderness after months of searching, police zero in on a local family man living a double life that no one suspects.
A rash of young men goes missing around Chicago during the 1970s when bodies start washing up in the river, a pattern emerges a small piece of evidence leads police to the home of a model citizen, where his furnace puts the suspect in the hot seat.
In the 1990s, New York is on edge as a killer leaves coded clues at crime scenes and declares his compulsion to choose victims by their birth signs.
Investigators in East Baton Rouge, La., hunt for a serial murderer who carefully carves up and cuts the bodies of his victims after death.
Chaos descends on Phoenix as two serial killers compete for the media's attention and the bodies pile up faster than the police can investigate.
El Paso investigators race to track down a ruthless killer who is burying his victims in shallow desert graves, dead or alive.
A Houston killer taunts the media and authorities as he uses homemade ligatures to murder his victims.
A cold-blooded killer conceals his victims' bodies with trash, discarding them like garbage in the back alleyways of Los Angeles.
A gruesome, execution-style double murder of a young couple shakes a small mountain community in Eastern Tennessee with no evidence or DNA left at the crime scene, police rely on the rumor mill and their instincts to try and identify suspects.
When a string of elderly people are brutally murdered in their homes along the Mississippi River, a Task Force is formed to hunt down a serial killer before they can strike again.
In Florida, a devoted mother disappears into the night after tucking her daughter into bed investigators chase down a trail of leads that include multiple suspects, culminating in a horrifying discovery.
When a hardworking single mother with a history of heart issues is found dead on the front steps of her home, detectives assume she died of natural causes, but as the investigation progresses, it becomes clear foul play was involved.
Women are found brutally murdered and panic strikes Baton Rouge the city suspects a serial killer is on the loose in an example of police work at its finest, detectives lead investigators to an unlikely suspect hiding a dark secret.
A shooting in broad daylight in the city of Waterloo, Iowa leaves two dead investigators Camarata and Moller follow a trail of bloody footprints to a list of suspects and an unexpected lead from a knowledgeable confidential informant.
A mother of two disappears after a night out at a local bar in New Mexico investigators race the clock in the hopes of finding her alive, and are eventually stunned by what they uncover.