In 1996, Derrick Duehren returned to find his Oregon home burned to the ground. His wife's charred remains were later found in the rubble.
A girl claimed she had been abducted. She recounted what happened but things didn't add up to police.
The victim had been sexually assaulted and stabbed to death on the beach. A pair of men's tennis shoes was discovered near her body.
The body of an attractive young woman was found a mile from her abandoned car. Police were especially concerned when they realized the victim had come to them for protection just two weeks earlier.
When a woman went missing, friends and family were determined to find her. Their worst fears were confirmed weeks later when her body was discovered.
In 2007, Shamaia Smith disappeared from the strip club she worked at in East Hartford, CT. Police look at various customers of the strip club, but focus on local businessman Kenneth Otto.
Paul Gruber's daughter suspected something was wrong when she received birthday cards addressed from her father, but written in a stranger's handwriting.
Tracey Frame, 35, was convicted of killing David Nixon in April 2002 after he planned to end their relationship.
A killer made great effort to obscure the shoe impressions left when he tracked blood on the floor, but he ended up creating new incriminating evidence...
In 2003, Tiffany Rowell and three of her friends were brutally murdered in affluent Clear Lake, Texas.
Responding to a 2008 garage fire, Illinois emergency response discovered a man crushed beneath a truck.
In 2006, Darlene VanderGiesen received threatening emails and then disappeared. Tracking the source of the emails led police to the home of Daphne Wright, where they believe a murder was committed.
An assistant manager of a Florida steakhouse is stabbed to death. It appears to be a robbery gone wrong.
In 1999, Patrick McRae was found dead in his Des Moines home and the crime scene was awash with blood.
Rachael Mullenix, 19, was convicted of stabbing her mother and then packing her bloodied corpse in a box.
Two suspects are linked to a murder by bloodstained boots and a gun, but the owner of the items says he has never met the victim.
When a college student is reported missing, police believe their investigation will be like countless others.
A skeleton was discovered in the North Carolina marshlands. Investigators learned she'd been dead for months.
In 2005, David Castor suffered a slow, agonizing death over a period of days. His wife maintained it was suicide, even though it was done with antifreeze.
A fireman died from what appeared to be heart disease, but his family was skeptical of the cause of death.