In 2000, the body of exotic dancer Rachel Siani was found beneath a New Jersey bridge. Investigators wondered if she had committed suicide.
An investigation into the murder of a World War II veteran slowed to a halt when the prime suspect had a solid alibi. But a lucky break led to a shady character who wore distinctive boots.
When a college co-ed vanished without a trace, her fellow students were concerned about her safety and their own.
The prime suspect had a criminal record and his driver's license was found at the scene of a brutal double homicide.
A security guard disappeared from his post without a trace his remains were found a year later in a remote camp site.
In 2006, Nevada politician Kathy Augustine died mysteriously during a hard-fought re-election campaign and the medical examiner could neither isolate the cause of death.
When a man's story of a killing contradicted physical evidence, investigators turned to forensic science.
A woman appears to have lost control of her SUV and plunged down an embankment into a shallow creek. But investigators suspect foul play when they find snowy footprints leading from the crime scene.
When a wealthy socialite died after falling down the stairs, witness accounts contradicted evidence. Investigators employed a physicist and an expert in accident reconstruction.
The crime scene was especially violent: A couple had been shot to death. Was their teenage daughter complicit?
A young woman is stabbed more than 100 times. The killer leaves DNA behind, but investigators must play a cat-and-mouse game to obtain a suspect's DNA to match.
A wealthy man and his wife were attacked by three masked men outside their luxurious Louisiana home. He was shot dead and she was forced to open their hidden safe.
When court clerk Peter Porco doesn't report to his work in November 2004, a courts officer is ordered to the Porcos' family home in Bethlehem, NY.
In 1986, Gary Dale Larson was stabbed to death in his Edmond, Oklahoma home and then the killer sexually assaulted Larson's girlfriend Janet Haynes.
When a college co-ed vanished without a trace, her fellow students were concerned about her safety and their own.
Tracey Frame, 35, was convicted of killing David Nixon in April 2002 after he planned to end their relationship.
In 2008, the body of Colorado real estate developer Alan Helmick was found by his wife, Miriam, who then became the prime suspect.
A family break turns into a nightmare when the wife is found face-down in a lake with no idea whether it was murder, an accident or suicide, police turn to a new forensic technique.
A serial rapist is on the loose in a Texas town. No one knew where he'd strike next, but the audacity of his attacks and the escalation of violence against his victims made finding him imperative.
The victim had been sexually assaulted and stabbed to death on the beach. A pair of men's tennis shoes was discovered near her body.