A bullet-riddled car, a missing driver, and no witnesses, an ambush or a random attack the clue was something so tiny, it was measured in millionths of a meter.
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When a college student is reported missing, police believe their investigation will be like countless others.
The crime scene was especially violent: A couple had been shot to death. Was their teenage daughter complicit?
A college senior was found raped and murdered near an unpaved footpath used by students to walk from one side of campus to the other.
In 1996, Virginia Beach police arrive at the Makdessi apartment to find Elise Makdessi and her lover dead.
In 2006, Nevada politician Kathy Augustine died mysteriously during a hard-fought re-election campaign and the medical examiner could neither isolate the cause of death.
In the 1990s, the media dubbed Richard Rogers the "Last Call Killer" because he targeted men in gay bars.
When a dedicated, well-respected teacher disappeared, police had to determine if she'd gone on vacation without telling anyone, or if she was the victim of foul play.
The medical examiner ruled a death an accident, but the detectives thought the evidence indicated otherwise.
In 2004, Rebecca Barney and her soon-to-be ex-husband Fred were found shot to death in their Tulsa, Oklahoma, home, which had been set on fire.
How did the stalker obtain the security system code for his victim's home? How did he steal her personal photographs? Police needed answers and they found them in the most unlikely of places.
A Russian immigrant is found dead and a strange phone call to his office is the only lead investigators have.
When a wealthy socialite died after falling down the stairs, witness accounts contradicted evidence. Investigators employed a physicist and an expert in accident reconstruction.
Seattle police had no suspects in the violent murder of post-grunge singer, Mia Zapata. More than a decade passed before the evidence could be used by forensic scientists to identify the killer.
In 1993, young mother Tammy Tatum was sexually assaulted and murdered in her Longmont, Colorado apartment.
The medical examiner ruled a death an accident, but the detectives thought the evidence indicated otherwise.
In 2001, Ginger Hayes and her infant son Nicholas were abducted during a carjacking and the crime had been reported by a witness within minutes of occurrence.
In 2003, Tiffany Rowell and three of her friends were brutally murdered in affluent Clear Lake, Texas.
An 82-year-old woman was found dead. Clues on the victim's body would tell police what happened that night.
A man was killed in a car crash, but the evidence led investigators to believe it was not an accident.
When a college co-ed vanished without a trace, her fellow students were concerned about her safety and their own.
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