Pride and the team take on a group of dirty cops when they discover that a murder victim was also a key witness in multiple excessive force cases Tammy faces the reality of being in a new relationship.
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Sebastian calls the team to assist with a possible kidnapping case when a dignitary's son he was assigned to protect disappears from a local concert venue.
Following a natural gas explosion at a movie theater, the team discovers the gas company has been hacked and more explosions could be triggered.
Lasalle hopes to avenge his brother's murder by tracking a drug ring in Alabama he believes is responsible when Pride assists with the case, he crosses paths with Eddie Barrett, an elusive individual who knows more than he is sharing.
Navy Lt. Max Landry asks the New Orleans field office for help when he suspects his girlfriend is a spy Lasalle faces another devastating dead end as he searches for his brother's last known whereabouts.
The team uncovers a sinister plot by a private detention center contracted by the government to house undocumented immigrants Lasalle and Sebastian travel to Alabama to search for Lasalle's missing brother.
Pride travels to New York City after new DNA evidence is linked to a 20-year-old cold case from his past.
A Navy pilot says she saw an unidentified object prior to a private plane crash Pride suffers from insomnia and nightmares as a result of being kidnapped and drugged last year.
When Elvis Bertrand's "daughter" is linked to a murder case, he asks Pride to prove her innocence.
A Navy lieutenant from a well-connected and affluent family has a fatal fall down a flight of stairs at a charity gala the team investigates whether his death was an accident or foul play.
The NCIS team investigates the murder of Patton's friend, a former Navy SEAL gunned down in a drive-by shooting while Patton watched.
After a reshuffling of assignments, Pride returns to the New Orleans office during the investigation of a missing petty officer.
After an elusive terrorist with a personal vendetta against Hannah resurfaces, she and her family are placed in protective custody while the team searches for the suspect.
The team investigates multiple murders tied to a construction company that creates an experimental chemical that strengthens sea walls evidence from Hannah's previous mission in Oman is used against her.
Walter takes a perilous swim to rescue a woman trapped in the La Brea tar pits Paige's mother maximizes Ralph's troop cookie sales.
McGarrett and Kono suspect that an abused young girl may be the victim of a sex trafficking ring on the Island Chin and Grover investigate a murder at a sober living facility.
After tracking down the missing uranium, which has been used to build a bomb in the middle of the jungle, McGarrett and Danny must move the explosive material through treacherous terrain before it detonates.
The Five-0 must once again engage in the twisted mind games of serial killer Dr. Madison Gray when she arrives at the HPD covered in blood that matches Alicia Brown's.
While McGarrett and Danno celebrate Valentine's Day with their girlfriends, the Five-0 team investigates the murder of a man taking a class on how to meet women.
While working a murder case, Five-0 discovers that a former Nazi war criminal may be hiding out in an old leprosy colony in Hawaii.
The team faces a contentious U.S. Marshall after a murder suspect escapes capture and looks for asylum in the sovereign land that belongs to the Nation of Hawaii.
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