As she struggles through the Scoville onslaught, Charlize Theron teaches Sean some South African slang, breaks down her reality-TV obsession and takes the spiciest Rorschach test in history.
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Neil Patrick Harris is an Emmy-winning actor who has entertained audiences for decades, on everything from acclaimed sitcoms to Broadway shows.
Hollywood vet Rob Lowe takes on the wings of death and discusses "West Wing" lore, comedy legends and the most overrated Thanksgiving sides.
Pete Holmes is the star & creator of "Crashing" and host of the "You Made It Weird with Pete Holmes" podcast.
Watch how Matthew McConaughey fares against the wings of death while answering questions about his writing process, what makes romantic comedies work and how helpful New Yorkers really are.
Dustin "The Diamond" Poirier takes on one of his toughest opponents yet: the wings of death! How do our sauces stack up to Poirier's very own hot sauce, Poirier's Louisiana Style?
LL Cool J is a two-time Grammy Award-winning artist, rap trailblazer and recent inductee to the Rock & Roll Hall of Fame.
In between painful fits of laughter, Danny Brown manages to share some top-shelf anecdotes about the Gathering of the Juggalos, 50 Cent's fashion tips and his beloved cats.
Tom Holland began his career at 12 years old and he's now one of Hollywood's biggest box office draws.
Pete Holmes is the star & creator of "Crashing" and host of the "You Made It Weird with Pete Holmes" podcast.
Winterfell legend Maisie Williams battles the (vegan) wings of death and discusses everything from appearing on Binging with Babish to "Game of Thrones" myths and that time Drake shouted her out at the Billboard Music Awards.
Malcolm Gladwell is the author of five NYT bestsellers, including 'The Tipping Point,' 'Blink' and 'Outliers.'
Academy Award-nominated actor Josh Brolin takes on the wings of death and discusses working with the Coen Brothers, growing up on punk rock and his favorite TV shows of all time.
Kid Cudi is a Grammy Award-winning artist and multi-hyphenate entertainer. He takes on the wings of death while discussing his brand-new album and animated TV special of the same name.
Can Neil keep his facts straight while battling the heat of Zombie Apocalypse and Mad Dog 357? Tackling everything from Obama selfies to Kanye West lyrics along the way.
Lover of anime Thundercat reveals the cartoons with the best theme songs, video game soundtracks, Marvel movies, his bass-playing days with Suicidal Tendencies, his love of bowling and the first time he met Sean in Los Angeles at The Comedy Store.
Mackie takes on the wings of death and drops knowledge about authentic New Orleans food, the rap bonafides of William Shakespeare and why Best Supporting Actor is the most coveted Academy Award.
Paris discusses bottle service scams, paparazzi evasion tactics, her relationship with the media and the art of 'sliving' (slaying + living) as she takes on the wings of death.
In between "America's Next Top Model" anecdotes and expert breakdowns of the modeling industry, Ty Ty drops a fire rap verse, critiques Sean Evans' head shots, stress-eats ice cream, strikes hot sauce-inspired poses and so much more.
Queen of comedy Leslie Mann takes on the wings death and calls out Hot Ones creator Chris Schonberger.
Paul Dano is an actor you know from his acclaimed performances in films like "The Batman," "Little Miss Sunshine," "There Will Be Blood" and many more.
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