When a wealthy socialite died after falling down the stairs, witness accounts contradicted evidence. Investigators employed a physicist and an expert in accident reconstruction.
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Police don't have a basis for comparison to match shoe impressions, blood drops and DNA evidence from a murder scene.
Volunteers and police spend weeks searching for a missing girl. A psychic later leads them to a field where the body was found.
Security cameras in a casino tracked a young woman's movements until shortly before she disappeared. She was never seen again.
After the suspect was convicted of murder, he maintained his innocence through his 25 years in prison.
The victim had ingested a massive amount of cyanide. An unlikely clue - a flaw on a mailing envelope - exposed a murderer who was willing to kill innocent people.
In 2007, Shamaia Smith disappeared from the strip club she worked at in East Hartford, CT. Police look at various customers of the strip club, but focus on local businessman Kenneth Otto.
In 2006, Texas real estate agent Sarah Anne Walker was found brutally murdered in a model home.
Two suspects are linked to a murder by bloodstained boots and a gun, but the owner of the items says he has never met the victim.
In 2004, nursing student Tamika Huston went missing from her Spartanburg, South Carolina home. A tip led detectives to her car, where they found an unknown house key that could help solve the case.
A man was killed in a car crash, but the evidence led investigators to believe it was not an accident.
When DNA proves that a man who practically admits to a brutal attack is innocent, police wonder why he is willing to take the blame.
A woman appears to have lost control of her SUV and plunged down an embankment into a shallow creek. But investigators suspect foul play when they find snowy footprints leading from the crime scene.
Kathy Lorick was murdered on a Concord, California jogging trail while talking to her husband on her phone.
A murder trail turned cold, until police got a call from a woman whose husband, Gerald Powers, had a criminal past and a fondness for Chevy Berettas.
When the number of bloodstains at a scene were abnormal, it was up to forensic scientists to find out why.
The prime suspect had a criminal record and his driver's license was found at the scene of a brutal double homicide.
In 2006, Darlene VanderGiesen received threatening emails and then disappeared. Tracking the source of the emails led police to the home of Daphne Wright, where they believe a murder was committed.
A millionaire and his family were executed in their own home. For three years, the murders went unsolved. Finally, a box of ammunition and some fluorescent fibers revealed the ultimate betrayal.
A young woman attends evening church services... then disappears. When her abandoned car is found, the tank is empty and a gas can she kept in her trunk for emergencies is missing.
In 2000, construction manager Darrell North was found dead in his work trailer in Ft. Worth, Texas. When investigators arrived, they found that he had been stabbed 46 times.
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