Five

Bob Newhart as Dr. Roth Ava Acres as Pearl at age 7 Ginnifer Goodwin as Charlotte Romy Rosemont as Lynne Jenifer Lewis as Maggie Jeanne Tripplehorn as Pearl Josh Holloway as Bill Jeffrey Tambor as Danny Ravi Patel as Dr. Desai Kirk Baily as Scott Kathy Najimy as Rocky Annie Potts as Helen Taylor Kinney as Tommy Josh Dallas as Henry Patricia Clarkson as Mia Lyndsy Fonseca as Cheyanne Emily Skinner as Sally Carla Gallo as Laura David Eigenberg as Lenny Rosario Dawson as Lili Aisha Hinds as Bernice Austin Nichols as Edward Xander Berkeley as Peter Alan Ruck as Sam Jarente Jennifer Morrison as Sheila Tony Shalhoub as Mitch Tracee Ellis Ross as Alyssa Scott Wilson as Bill (Older)

Sian Richards Key Makeup Artist Paula Wagner Executive Producer Lorne Balfe Original Music Composer Demi Moore Director Nellie Nugiel Producer Lynzee Klingman Editor Kristin Hahn Executive Producer Penelope Spheeris Director Jennifer Aniston Director, Executive Producer Zene Baker Editor Tami Reiker Director of Photography Alicia Keys Director Patty Jenkins Director Marta Kauffman Creator, Executive Producer Eric Alan Edwards Director of Photography Whitney James Makeup Department Head Mary Claire Hannan Costume Design